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· Did you know that one million bases is called a megabase(Mb)?
 

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DNA

Within each chromosome lies a gigantic molecule of chemical known as deoxyribonucleic acid or DNA in short. The DNA is very tightly packed like a spring. Each chromosome can be regarded as a very long piece of DNA which if fully stretched would be 2 metres long!

How does a DNA molecule look like? The structure of the DNA molecule was first discovered by two scientists known as James Watson and Francis Crick in 1953. It looks like a very long twisted ladder known as a double helix (See diagram)

The two sides of the ladder are made of sugar phosphate. The rungs of the ladder are the most important because they give the cell its information. Each rung is split into half, and each half of the rung is made of a nitrogenous chemical, which can either be adenine, guanine, cytosine or thymine. They are typically referred simply as A, G, C or T. These chemicals join in the middle and these bases always occur in pairs. A always joins to T, and C always joins to G. A base pair or bp in short refers to either a pair of A and T or a pair of G and C

A sugar and phosphate (found on the side of the ladder) and one nitrogenous base (found on the rungs of the ladder) is called a nucleotide. Each strand of the double helix therefore contains many nucleotides.

 

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