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Encountering Microgravity
How Astronauts Feel in Mircogravity
Countermeasures to deal with Microgravity

How Astronauts Feel in Mircogravity

Astronauts have the following feelings when they first encounter microgravity:
- Nausea
- Disorientation
- Headache
- Loss of appetite
- Congestion

The longer they stay in microgravity, the more their muscles and bones weaken. These feelings are caused by changes in various systems of the body. Let's discuss how the body responds to microgravity.

Spacesick
Before dicussing spacesick, let's talk about how people sense position and motion. Orientation and motion are sensed by using the vestibular system, which is located in the upper portion of the inner ear.
How the vestibular system senses orientation with respect to gravity?
- It has otolithic organs that contain crystals of calcium carbonate
- The crystals are attached to hair-like sensory nerve cells in three orientations (x-, y-, z-axes)

1. When you bend your head in different directions (forward, backward, sideways), gravity pulls on the crystals that are oriented in the direction of the pull.
2. The affected crystals stimulate the attached hair cells to send nerve impulses to the brain.
3. The brain interprets these signals to find out which way the head is oriented in space.

How the vestibular system sense motion?
- There are three semicircular canals for sensing motion, specifically acceleration.
- They are oriented at right angles to one another, and each is in one of the three directions (x-, y- or z-axis).
- They contain fluid called endolymph and hair-like sensory nerve cells.
1. As your head accelerates in a given direction, the endolymph lags behind because of its initial resistance to change in motion (inertia).
2. The lagging endolymph stimulates the appropriate hair cells to send nerve signals to the brain.
3. The brain interprets them to find out which way the head has moved.
The nausea and disorientation that you feel are like your experience in a drop on a roller coaster ride, only you have that feeling constantly for several days.
This is the feeling of space sickness, or space motion sickness, which is caused by conflicting information that your brain receives from the eyes and the vestibular organs located in the inner ear. The eyes can see which way is up and down inside the shuttle. However, because The vestibular system relies on the downward pull of gravity to tell the astronauts which way is up versus down and in which direction they are moving, it does not function in microgravity. So the eyes may tell your brain that they are upside-down, but the brain does not receive any interpretable input from the vestibular organs. Their confused brain produces the nausea and disorientation, which in turn may lead to vomiting and loss of appetite. Fortunately, after a few days, the brain adapts to the situation by relying solely on the visual inputs, and they begin to feel better. And NASA has produced medication patches to help astronauts deal with the nausea until their bodies adapt.
Puffy Face
Normally, when someone standing upright, gravity pulls blood downward so it pools in the veins of the legs. In microgravity, the blood shifts from the legs into the chest and head, so the face will feel full and the sinuses will feel congested, which may lead to headaches and space motion sickness. Also, the face tends to get puffy and the sinuse swell. When the blood shifts to the chest, the heart increases in size and pumps more blood with each beat. The kidneys respond to this increased blood flow by producing more urine. Moreover, the increase in blood and fluid decease anti-diuretic hormone (ADH) secretion by the pituitary gland, which makes people less thirsty. Therfore, astronauts do not drink as much water as they might on the Earth. After returning to the Earth, gravity will pull those fluid back down to the legs and away from the head, which will cause the people to feel faint when standing up. But the astronauts will also begin to drink more, and the fluid levels will return to normal in a couple of days.

Space Anemia
As the kidneys eliminate the excess fluid, they also decrease their secretion of erythropoietin, a hormone that stimulates red blood-cell production by bone marrow cells. The decrease in red blood-cell production matches the decrease in plasma volume so that the hematocrit (percentage of blood volume occupied by red blood cells) is the same as on Earth. Upon the return to Earth, the erythropoietin levels will increase, as will the red blood-cell count.

Weak Muscles and Bird Legs
When astronauts are in microgravity, their body adopts a "fetal" posture -- they crouch slightly, with their arms and legs half-bent in front of them. In this position, they do not use many of their muscles, particularly those muscles that help them stand and maintain posture (anti-gravity muscles). This will make their muscles change, leading to the decrease in mass of the muscles, which contributes to the "bird leg" appearance. The muscle fiber types change from slow-twitch to fast-twitch. The body no longer needs slow-twitch endurance fibers, such as those used in standing. Instead, more fast-twitch fibers are needed as they push themselves quickly off of space station surfaces. The longer they stay on the station, the less muscle mass they will have. This loss of muscle mass makes them weaker, presenting problems for long-duration space flights and upon returning home to Earth's gravity.

Brittle Bones
On Earth, the bones support the weight of the body. The size and mass of the bones are balanced by the rates at which certain bone cells (osteoblasts) lay down new mineral layers and other cells (osteoclasts) chew up those mineral layers. In microgravity, as the bones do not need to support the body, all of the bones, especially the weight-bearing bones in the hips, thighs and lower back, are used much less than they are on Earth. In these bones, the rate at which the osteoblasts deposit new bone layers is reduced (but no one knows exactly why, though it is thought that changes in force and stress are somehow involved), while the rate at which osteoclasts chew up bone stays the same. As a result, the size and mass of these bones continue to decrease as long as the astronauts remain in microgravity, at a rate of approximately 1 percent per month. These changes in bone mass make the bones weak and more likely to break upon they return to Earth's gravity. It is not known how much of the bone loss is recoverable upon return to Earth, although it is probably not 100 percent. These changes in bones may limit the duration of space flights.

Kidney Stones
The blood's calcium concentration increases slightly as the bones get chewed up by osteoclasts (which is described previously). The kidneys must get rid of the excess calcium, which makes them susceptible to forming painful kidney stones.

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