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Genetically modified food is food which contains ingredients that have had their genetic structure modified in order for them to grow faster, bigger or be more resistant to pests when growing. Many people are unhappy about genetically modified foods because they believe they may be harmful to health and because not enough tests have been done into its safety.

What harmful effects might turn out to be associated with the use or release of genetically engineered organisms?

This is not an easy question. Being able to answer it depends on understanding complex biological and ecological systems. So far, scientists have identified a number of ways in which genetically engineered organisms could potentially adversely impact both human health and the environment. Once the potential harms are identified, the question becomes how likely are they to occur. Here are the some examples of the potential adverse effects of genetically engineered organisms may have on human health. Most of these examples are associated with the growth and consumption of genetically engineered crops.

[ New allergens in the food supply ]

Transgenic crops could bring new allergens into foods that sensitive individuals would not know to avoid. An example is transferring the gene for one of the many allergenic proteins found in milk into vegetables like carrots. Mothers who know to avoid giving their sensitive children milk would not know to avoid giving them transgenic carrots containing milk proteins. A study by scientists at the University of Nebraska shows that soybeans genetically engineered to contain Brazil-nut proteins cause reactions in individuals allergic to Brazil nuts.

Genetic engineering routinely moves proteins into the food supply from organisms that have never been consumed as foods. Some of those proteins could be food allergens, since virtually all known food allergens are proteins. Recent research substantiates concerns about genetic engineering rendering previously safe foods allergenic.

[ Antibiotic Resistance ]

Genetic engineering often uses genes for antibiotic resistance as "selectable markers." Early in the engineering process, these markers help select cells that have taken up foreign genes. Although they have no further use, the genes continue to be expressed in plant tissues. Most genetically engineered plant foods carry fully functioning antibiotic-resistance genes.

The presence of antibiotic-resistance genes in foods could have two harmful effects. First, eating these foods could reduce the effectiveness of antibiotics to fight disease when these antibiotics are taken with meals. Antibiotic-resistance genes produce enzymes that can degrade antibiotics. If a tomato with an antibiotic-resistance gene is eaten at the same time as an antibiotic, it could destroy the antibiotic in the stomach.

Second, the resistance genes could be transferred to human or animal pathogens, making them impervious to antibiotics. If transfer were to occur, it could aggravate the already serious health problem of antibiotic-resistant disease organisms.

[ Production of new Toxins ]

Many organisms have the ability to produce toxic substances. For plants, such substances help to defend stationary organisms from the many predators in their environment. In some cases, plants contain inactive pathways leading to toxic substances. Addition of new genetic material through genetic engineering could reactivate these inactive pathways or otherwise increase the levels of toxic substances within the plants.

[ Enhancement of the Environment for Toxic Fungi ]

Although for the most part health risks are the result of the genetic material newly added to organisms, it is also possible for the removal of genes and gene products to cause problems. For example, genetic engineering might be used to produce decaffeinated coffee beans by deleting or turning off genes associated with caffeine production. But caffeine helps protect coffee beans against fungi. Beans that are unable to produce caffeine might be coated with fungi, which can produce toxins. Fungal toxins, such as aflatoxin, are potent human toxins that can remain active through processes of food preparation.

[ Unknow Harms ]

As with any new technology, the full set of risks associated with genetic engineering have almost certainly not been identified. The ability to imagine what might go wrong with a technology is limited by the currently incomplete understanding of physiology, genetics, and nutrition.

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