Translation
Definition: Translation is the process in
which the genetic information on a mRNA molecule is
made use of to make proteins.
In the last section, we mentioned
that genetic codes on DNA in nucleus is copied
onto a mRNA molecule. The mRNA
then move out of the nucleus. Here, in the
cell's cytoplasm, the proteins coded on the mRNA
molecule will be synthesized.
Before we look into
the actual process of translation, let's talk
about how is the genetic information coded in
our cells. The bases on a mRNA are read in
groups of 3. For example, a sequence CCGGAUCCAAGA
will be read as CCG, GAU, CCA, AGA. Each
of the triplets will represent one amino acid.
There are 20 different amino acids in man, and
these link together to form proteins. Difference
in proteins occurs when the amino acids are
arranged in different sequences.
During Translation, a ribosome
will attach itself onto the strand of mRNA
molecule waiting to be translated. It will cover
a single triplet code at a time. The Ribosome
has sockets where tRNA molecules can be
inserted. The tRNA molecules are linked to a
specific amino acids at one one end, and has 3
bases at the other end. The tRNA molecule whose
bases are able to pair with the triplet code on
mRNA can enter the socket, and release its amino
acid before leaving the socket. The ribosome
will move on to the next triplet, and another
tRNA will be able to enter the socket. The
process repeats itself until the end of the mRNA
molecule. The amino acids that are released by
the tRNA will join together to form a linear
chain. The sequence of amino acids is determined
by the sequence of triplets on the mRNA
molecule.
Relating
Topics
- Dominant
and Recessive Alleles
- Examples
of Traits
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