Notes: Cellular Respiration

Terms to know:

Dehydrogenase is a collective term for any enzymes involved in Cell Resp.
Negative feedback (feedback inhibition) is how anabolism stops catabolism.
Biosynthesis:  food must also provide the carbon for the cell's molecules.

Three Steps to ATP Creation
glycolysis
krebs cycle (TCA)
cytochrome chain
catabolic

glucose becomes 2
pyruvates in the cytosol

[details]

 catabolic

derivative of pyruvate
becomes carbon dioxide
in mitochondrial matrix

[details]

 anabolic (stores energy)

NADH+FADHATP

[details]

Stuff other than glucose enters cellular respiration:

Starch and glycogen can.  Proteins can enter only after deamination (amine group removal).  Fats digested into glycerol can enter as can fatty acids (but they must be converted to Acetyl CoA before entering TCA)

Negative Feedback

When ATP concentration down, respiration speeds up.  When ATP concentration up, respiration slows down.  
e.g.,  Phosphofructokinase is an allosteric enzyme in step 3 of glycolysis that ATP inhibits and ATP activates.  Citrate also inhibits it keeping glycolysis and Krebs synchronized.

Biosynthesis

Proteins can be used as is; no modification needed; just insert it into a protein.  Compounds can enter glycolysis/krebs then be diverted to synthesis.  Humans can make 1/2 of the 20 amino acids by modifying compounds siphoned from TCA.