Communication via proteins between ECM and the interior cell
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An extracellular molecule (first messenger or FM)
binds to a specific receptor protein
(R1P).
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R1P activates a
relay protein (R2P).
-
R2P stimulates an
effector protein (EP).
-
EP produces an active
2nd messenger (A2M) from an inactive 2nd messenger
(I2M).
-
A2M triggers various
cellular responses (CRs)
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