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Acquired Immune Deficiency Syndrome
(AIDS) is a specific group of diseases or conditions
that result from reduction in the action of the immune
system due to infection with
the human immunodeficiency virus (HIV).

In other words, HIV is the virus that causes AIDS.
A person infected with HIV gradually loses immune function along
with certain immune cells called CD4 T-lymphocytes or CD4
T-cells, causing the infected person to become vulnerable to common ailments. With the loss of immune function, a clinical
syndrome
(a group of various illnesses that together characterize a disease)
develops over time and eventually results in death due to opportunistic infections
(infections by organisms that do not normally cause disease except in
people whose immune systems have been greatly weakened) or cancers.
A person can remain HIV-positive
for more than ten years without developing any of the clinical illnesses
that define and constitute a diagnosis of AIDS.
HISTORY
In the early 1980s deaths by opportunistic infections,
previously observed mainly in organ transplant
recipients receiving therapy to suppress their immune responses, were
recognized in otherwise healthy homosexual
men. In 1983 French cancer specialist Luc Montagnier and scientists at
the Pasteur Institute in Paris isolated what appeared to be a new human retrovirus—a
special type of virus
that reproduces differently from other viruses—from the lymph node of
a man at risk for AIDS. At the same time, scientists working in the laboratory of American
research scientist Robert Gallo at the National Cancer Institute in
Bethesda, Maryland, and a group headed by American virologist Jay Levy
at the University of California at San Francisco isolated a retrovirus
from people with AIDS and from individuals having contact with people
with AIDS. All three groups of scientists isolated what is now known as
human immunodeficiency virus (HIV), the virus that causes AIDS.
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