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Fermentation
Production of ATP through the Krebs Cycle and Electron Transport Chain require
the presence of oxygen. The cell's ability to produce ATP in the absence of
oxygen can be traced back to the first cell, when there wasn't molecular oxygen
available to the cells. Therefore, anerobic metabolism (a.k.a. fermentation) was
evolved. Today, many anerobic organisms and special types of cells such as
muscle tissue (which occasionally function without oxygen) use fermentation to
derive their energy. Since glycolysis occurs
without oxygen, it is able to convert glucose into pyruvate. Subsequently, the
pyruvate is converted to either ethanol + CO2 (in yeast) or lactate (in muscle)
via fermentation. This further reduction of pyruvate gives off a little more
energy for the cell to utilize. A buildup of lactate, such as when you exercise
hard, causes the soreness you feel in the muscle.
The fermentation reactions can be described as follows:
Pyruvate + NADH2+
-> lactic acid + NAD+
or
Pyruvate + NADH2+ -> ethanol + CO2 + NAD+ |
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