Step 2: RNA Translation
After the mRNA has been transported to the rough
endoplasmic reticulum, it is fed into the ribosomal translation
machineries. Ribosomes begins to read the mRNA sequence from the 5` end to the
3` end. To convert the mRNA into protein, tRNA is used to read the mRNA
sequence, 3 nucleotides at a time.
Amino acids are represented by codons, which are 3-nucleotide RNA sequences. The mRNA sequence is matched three
nucleotides at a time to a complementary set
of three nucleotides in the anticodon region of the corresponding tRNA molecule.
Opposite the anticodon region of each tRNA, an amino acid is attached and as the
mRNA is read off, the amino acids on each tRNA are joined together through peptide