Excitable Cells

These are cells that have the ability propagate and spread action potentials to surrounding cells.

Cardiomyocytes

These are the muscle cells of the heart, each one physically contracting to cause the heart muscle to shorten. They are relatively very large cells (30x30x150 micron), constitute up to 80% of the heart volume and have an elongated, brick-like appearance.

Isolated Cardiomyocyte

Smooth Muscle Cells

These cells are located inside the walls of large arteries and arterioles. Their primary purpose is to regulate vessel diameter by contracting and relaxing.

Pacemaker Cells

The pacemaker cells make up the two (S-A and A-V) nodes of the heart. These cells spontaneously depolarize (as a result of their high membrane permeability to sodium ions) and generate action potentials at regular intervals.

Purkinje Cells

These are very large, elongated muscle cells which rapidly (speeds up to 4 m/s) spread impulses from the A-V node to the ventricles. This allows for an almost immediate transmission of the electrical impulse throughout the entire cardiac muscle.

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