Microbiology terms - N


natural killer (NK) cell
A specialized lymphocyte that recognizes and destroys foreign cells or infected host cells in a nonspecific manner.
necrosis
Damage of living tissues due to infection or injury.
nicotinamide adenine dinucleotide (NAD)
An important coenzyme, functioning as a hydrogen carrier in a wide range of redox reactions; the H is carried on the nicotinamide residue. The oxidized form of the coenzyme is written NAD+, the reduced form as NADH (or NADH+H+)
nicotinamide adenine dinucleotide phosphate (NADP)
An important coenzyme, functioning as a hydrogen carrier in a wide range of redox reactions; the H is carried on the nicotinamide residue. The oxidized form of the coenzyme is written NADP+, the reduced form as NADPH. Many oxidoreductases are specific for either NAD or NADP, although some can function with either. As a broad generalization, NADP is more commonly associated with biosynthetic reactions, NAD with catabolic and energy-yielding reactions.
nitrification
The conversion of ammonia (NH3) to nitrate (NO3-).
nitrifying bacteria
Chemolithotrophs capable of carrying out the transformations from NH3 to NO2- or NO2- to NO3-.
nitrogenase
The enzyme complex catalyzing the reaction of nitrogen fixation.
nitrogen fixation
Reduction of dinitrogen gas (N2) to ammonia (NH3) by the enzyme nitrogenase.
nodule (root nodule)
A tumorlike structure produced by the roots of symbiotic nitrogen-fixing plants. Contains the nitrogen-fixing microbial component of the symbiosis.
nomenclature
The system of naming things (e.g. organisms).
nonpolar
Possessing hydrophobic (water repelling) characteristics and not easily dissolved in water.
nonsense mutation
A mutation that changes a sense codon into one which does not code for an amino acid.
nonsulfur purple bacteria
A group of phototrophic prokaryotes containing bacteriachlorophylls a or b which grow best as photohetertrophs and have a relatively low tolerance for hydrogen sulfide (H2O).
northern blot
Hybridization of a single strand of nucleic acid (DNA or RNA) to RNA fragments immobilized on a filter. Compare with Southern and western blot.
nosocomial infection
Hospital-acquired infection.
nucleic acid
A polymer of nucleotides, see also DNA and RNA.
nucleic acid probe
A strand of nucleic acid which can be labeled and used to hybridize to a complementary molecule from a mixture of other nucleic acids. In clinical microbiology, short oligonucleotide of unique sequences used as hybridization probes for identifying pathogens.
nucleoid
The aggregated mass of DNA that makes up the chromosome of prokaryotic cells.
nucleoside
A nucleotide without the phosphate group.
nucleotide
A monomeric unit of nucleic acid, consisting of a sugar (ribose), a phosphate, and a nitrogenous base.
nucleus
A membrane-enclosed structure containing the genetic material (DNA) organized in chromosomes.
numerical taxonomy
The groupig by numerical methods of taxonomic units into taxa based on their character states.
nutrient
A substance taken by a cell from its environment and used in catabolic or anabolic ractions.
nutrient agar
The solid version of nutrient broth supplemented with agar.
nutrient broth
A general-purpose liquid basal medium composed of e.g. beef extract and peptone, which allows many types of microorganisms to grow.

Compiled by Tsute Chen, Converted by Ben Hoyt