Microbiology terms - D


defined medium
A medium whose exact chemical composition is quantitatively known. Compare with complex medium.
degeneracy
In relation to the genetic code, the fact that more than one codon can code for the same amino acid.
deletion
A removal of a portion of a gene.
denaturation
Irreversible destruction of a macromolecule, as for example the destruction of a protein by heat.
denitrification
Conversion of nitrate into nitrogen gases under anaerobic conditions, resulting in loss of nitrogen from ecosystems.
dental plaque
Bacterial cells encased in a matrix of extracellular polymers and salivary products, found on the teeth.
deoxyribonucleic acid (DNA)
A polymer of nucleotides connected via a phosphate-deoxyribose sugar backbone; the genetic material of the cell.
desiccation
Drying
dideoxynucleotide
A nucleotide lacking the 3'-hydroxyl group on the deoxyribose sugar. Used in the Sanger method of DNA sequencing.
differential medium
A medium which is used to differentiate different types of microorganisms based on their different e.g. colors or shapes of colonies. Examples of differential media are: Macconkey's agar and SS agar.
differentiation
The modification of a cell in terms of structure and/or function occurring during the course of development.
diplococcus
A pair of cocci.
diploid
In eukaryotes, an organism or cell with two chromosome complements, one derived from each haploid gamete.
disinfectant
An agent that kills microorganisms, but may be harmful to human tissue.
disproportionation
The splitting of a chemical compound into two new compounds, one more oxidized and one more reduced than the original compound.
DNA fingerpriting
Use of the techniques of genetic engineering to determine the origin of dDNA in a sample of tissue.
DNA library
A collection of cloned DNA fragments which in total contain genes from the entire genome of an organism; also called a gene library.
domain
1. The highest level of biological classification, superseding kingdoms. The three domains of biological organisms are the Bacteria, the Archaea, and the Eukarya.
2. Also used to describe a region of a protein having a distinct function.
doubling time
The time needed for a population to double. See also generation time.
downstream position
Refers to nucleic acid sequences on the 3'-side of a given site on the DNA or RNA molecule. Compare with upstream position.

Compiled by Tsute Chen, Converted by Ben Hoyt