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Implications and Costs

Implications

tab“... the Human Genome Project could easily be the most important organized scientific effort of mankind.” say M.R.C. Greenwood and Rachel E. Levinson in their article, “Expanding the Horizons of Biotechnology in the Twenty-First Century.” On one hand, the project involves so many people, and not only geneticists; rather the Human Genome Project relies on all scientific and technological backgrounds from physics and chemistry to engineering and robotics to computer science. Even sociologists, ethicists, and theologians are involved. Never before in the history of humanity have so many professionals united under a single scientific endeavor.

The project’s medical benefits are astounding as well. As each new gene is isolated, examined, and identified, we learn more and more about the human body and how it works on the microscopic and genetic levels. Diseases are more easily diagnosed. Sometimes, even before symptoms appear, doctors can identify at-risk patients simply by examining their genes. Gene therapy, correcting diseases via genetic engineering, can also cure more diseases now that more disease-causing genes have been located. In some cases, doctors no longer need to perform surgery; instead they can solve the problem by merely introducing healthy DNA.

Chromosomes

Image of human chromosomes
Image provided courtesy of Applied Imaging

Costs

tabThe estimated total cost of the Human Genome Project is a staggering $3 billion. Why does it cost so much? Well, consider all of the people and equipment involved: computers are needed to store the data; technicians are needed to maintain the computers, geneticists are needed to map the genome; laboratory equipment is required, and so forth. The US government provides most of the funds (other funds coming from big companies and other countries). In 1995, President Clinton proposed to Congress that $241 million be budgeted to the National Institute of Health and the Department of Energy who head the project (this amount includes money for actual research, not employee salaries). This amount is nearly $42 million more than the amount spent in 1994 and $171 million more than the amount in 1993. The project is clearly growing and demanding more attention.

Scientist

Scientist preparing agarose gel for seperating DNA fragments
Courtesy USDA ARS

tabThe project is also attracting the attention of those in the business sector. Each year, many new biomed companies emerge, hoping to capitalize from the new research.


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