Hereditary Corproporphyria (HCP)

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Hereditary Corproporphyria is an autosomal dominant inherited disorder that is similar to AIP.  HCP remains latent until an acute attack occurs. The symptoms are not present until after an attack. The acute attack causes both neurological and cutaneous manifestations.

Symptoms:

• Pruritis, edema, and other skin lesions may occur from exposure to visible light (sunlight). The porphyrins absorb large amounts of energy from sunlight, even   through window glass.
• Feces contains large amount of corproporphyrin III.
• Muscle weakness and paralysis
• Increased heart rate
• Pain in the trunk and back
• Hallucinations

HCP symptoms are similar to those of the AIP but less severe. The neurological symptoms are poorly understood for both of the porphyrias.