


Treating cancers
Most cancerous tissues consist
of rapidly dividing cells, which
can be seriously affected by ionising
radiation that damages their DNA.
DNA damage may result
in cellular destruction during cell
division.
Though cells have a mechanism to
repair the damaged DNA, cells which
are dividing rapidly have much less
time to have their DNA repaired,
thus resulting in preferential a patient with cancer being prepared for treatment
destruction of cancer cells.There are
several types of radiation therapy:
Brachytherapy: putting radioactive
sources into the tumor or close to it.
Cancers can be treated by inserting
hollow needles (made of iridium-
platinum alloy), with radioactive
radium sulphate inside, in a suitable
pattern, as to give a uniform dosage
to the tumor. A permanent implantation
of a radioactive source is also used to treat cancer. Gold-198 (with a half-life of 65 hours)
or iodine-125 (with a half-life of 60 days) are packed in some very tiny cylinders and
implanted in the cancerous area. These short-lived [radionuclides]deliver the dose to the
tumor and then promptly decay away.
High-intensity X-rays treatment
This is used for tumors deep inside the body or tumors in inoperable areas. The X-rays are
concentrated on the cancerous area to kill the cancer cells.
However, this sort of treatment can also kill normal cells which divide rapidly, such as the
hair cells, skin cells and blood cells. These cells are severely affected by radiation, this
explains why cancer patients taking these therapies suffer from hair loss. Since radiation
can cause so much harm to normal cells, these therapies are usually fractionated to allow
time for the damaged normal cells to repair.
Tracers
Tracers are weak [radioisotopes], which are injected into a system and can be traced through
the system with a detector.
It can be used to:
- estimate the blood volume of a patient
- view the structure of the blood vessels
of the patient
- locate the blood clots inside the body-by
injecting sodium-24 into the blood stream and finding out where
the flow stops
In addition, tracers are used for organ imaging. Certain organs in our body concentrate
certain types of chemicals, by injecting radioactive isotopes into the bloodstream, tumors
in a particular area can be detected and will be affected if that area concentrates that
radioactive isotope.
On the other hand, this can be used to obtain images of organs with a gamma camera.
The following table shows the corresponding location in which a particular chemical is
concentrated.
|
Chemical |
Location in
which chemicals are concentrated |
|
Iodine |
Thyroid gland |
|
Technetium |
Thyroid gland |
|
Xenon |
Lungs |
|
Phosphorous |
Cancerous tissue
|
|
Gallium-67 |
Cancerous tissue |
Therapy
A person receiving radiotherapy to treat cancer.
The illuminated disks indicate the areas that are to receive radiation.
Administration of radioactive iodine can be used to treat thyrotoxicosis (overactivity of the
thyroid gland). Since the thyroid gland concentrates the iodine, excess tissue of the thyroid
gland can be destroyed by beta emission. The dose is orally taken in a solution of sodium
iodide.
*back* (C) 1999 ThinkQuest Team 27954