In this project, we would like to investigate the effectiveness of crude scorpion
(Heterometrus longinamus) venom as a medicative cream which possibly can be
applied on the skin.
· This is due to the fact that venom cannot be taken orally or be injected into the
bloodstream (intra-veinous injections) Venom is comprised largely of proteins,
which would eventually be digested into amino acids in the digestive track if
taken orally, thus serving no purpose.
· Furthermore, if injected into the bloodstream, the venom may result in
localized swelling due to antibodies attacking the venom. But, if the venom
was to be applied on the skin itself, only a tiny amount of venom might enter
through the wound, and having less disastrous effect.
· In order for it order to be considered for use as a medicine, some aspects of the
action of venom would be tested. We hope to look into the following aspects of
of the venom :
1. Its antimicrobial properties, so that it can prevent the entry of
pathogenic bacteria into the open wound and causing
inflammation.
2. Its effect on nerves, because a decrease in nervous activity
would mean a decrease in the sensation of pain. The venom can
then be used as a mild anaesthetic to ease the pain of open
wounds.
3. Its effect on open wounds, because venom might or might not
cause secondary effects on wounds like inflammation or
envenomation.