MECHANISM OF ACTION

Sarin also functions along the same lines as nerve agents.In general, it too, inhibits the acetylcholine esterase enzyme in the human body's cholinergic nervous system.When such an enzyme is inhibited, the active site loses its specificity and will not be able to accommodate the complementary substrate (acetylcholine), form an ES-COMPLEX and break it down into simpler products.

In fact, it is usually based on this principle that nerve agents for chemical warfare are manufactued in the first place.

The initial early-warning symptoms include breathing difficulty,miosis,nausea,involuntary ,drowsiness and convulsions.Such symptoms vary among people and depends on the nature of the exposure to the toxic gas.

Sarin causes damage to the respiratory system and it should be known that its detoxification in human body is low.Death does not always come with a warning and can be a consequence of the symptoms due to Sarin exposure.

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