Cartilage from skin
till now, there was no viable replacement for
worn-out [cartilage]. For many athletes out there,
it meant having [osteoarthritis] for the rest of
first, it was thought possible to grow cartilage
cells in a culture and then replaced into the
joint. The cells that were needed to seed in this
case, came from the patient himself.
method was tried out, but there wasn't 100%
success and the risks included having to remove a
sizable portion of cartilage in order to seed the
Nicoll of the University of California seems to
have a solution.
took undifferentiated cells called fibroblasts
from the skin, and by simulating the conditions
of the womb, he transforms these cells into
cartilage-producing ones called chondrocytes.
chondrocytes are then transplanted into a matrix
which is porous. The matrix gives a place for the
cells to deposit the cartilage, and also moulds
them into the required shape.
the procedure has been perfected, this fresh
cartilage would be able to integrate with the
present body parts, and withstand the demands of
the human body.