Historically, people have always had difficulty reconciling the physical presence of a few pounds of grayish material in the skull with the range of thoughts, emotions, and memories of the human mind. This "mind-brain problem" has occupied generations of philosophers and, more recently, neurobiologists. Beginning with observations of patients with head injuries, processing to sophisticated surgical, physiological, and biochemical experiments, the outlines of how the brain creates the mind are beginning to emerge. Here, we will be able to touch upon only a few of the more fascinating features.