Kary B. Mullis
|(1944 - )
Mullis, born in Lenoir, North Carolina, attended the University of Georgia Tech for his undergraduate work in chemistry, and then obtained a Ph. D. in biochemistry from Cal Berkeley.
In 1983, working for Cetus Corporation, Mullis developed the Polymerase Chain Reaction, a technique for the rapid synthesis of a DNA sequence. The simple process involved heating a vial containing the DNA fragment to the split the two strands of the DNA molecule, adding oligonucleotide primers to bring about reproduction, and finally using polymerase to replicate the DNA strands. Each cycle doubles the amount of DNA, so multiple cycles increase the amount of DNA exponentially, creating huge numbers of copies of the DNA fragment.
Mullis left Cetus in 1986. For his development of PCR, he was co-awarded the Nobel Prize in chemistry in 1993. Mullis is currently doing HIV and AIDS research.
Copyright 1998 by team 24355 and Kayotic Development.