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          The nucleus of a cell contains the chromosomes. The chromosomes all contain nuclei acids, usually DNA which controls heredity in cells. Watch a DNA Video!

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              DNA is made up of a twisted double helix or ladder made of phosphates and sugars. The helix has steps made of four nitrogen bases that are paired; adenine with thymine and cytosine with guanine. Different organisms have different amounts of each base. Humans have more adenine than thymine. The way the bases are lined up on a twisted helix determines heredity traits or genes which are found lined up on different chromosomes. Just one gene can be made of hundreds of bases.

 

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Replication of DNA

        The replication of the chromosomes and DNA in mitosis is the key to genetic continuity. This is how DNA creats a copy of itself. First, the helix untwists itself as shown here.

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Then the bases of the DNA ladder begin to separate down the middle
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As the bases separate, other bases ( with sugars and phosphates attached ) float into the area of the opened ones and join with the exposed bases to eventually create two DNA helices necessary for two cells.
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Two identical DNA strands are made
 
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During DNA replication, occasional errors are made in the new DNA strand. These errors result in what we know as a mutation.

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CELLS  |  CHROMOSOMES  | DNA  |   QUIZ