The novel tells the story of Victor Frankenstein, a young medical student who obsessed with reversing death in humans, decides to create a body of the union of several corpses. The experiment is a success, the body on the table is alive and Victor understands what he created, he rejects his creating and runs away from the lab.
The monster (who does not have a name) is rejected by all human beings, so he fills himself of hatred and revenge. He chases Victor to Geneva and murders his younger brother, William. To recover from the loss, Victor goes to the mountains and this is where he meets again with the monster. The monster claims Victor for having abandoned him and asks him to create a partner fro him. At the beginning Victor agrees, but his remorse takes him to destroy his creation before giving her life, so the monster decides to avenge him.
Soon, the monster murders his best friend and then Elizabeth, his fiancé, on the wedding night. Due to the deaths, Victor's father also dies.
Victor, tired of his creation, seeks the monster until he reaches a boat in the Arctic. He dies soon after, then the monster comes in the same boat and finishes the story to the captain, ensuring him that he is determined to end his existence after leaving the boat.