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| Monogenic
| Type 2 diabetes is a form of non- insulin dependent diabetes. Type 2 Diabetes is the most common form of diabetes that accounts for 90 to 95% of all cases. It is prevalent in adults of 40 years or older. However Type 2 Diabetes has shown to be rampant in teens/adolescents. It was once thought to be common in adults, however this form of diabetes is now being seen in children as young as 7 years of age. Type 2 Diabetes goes through three main stages. The include insulin resistance, postprandial hyperglycemia and fasting hyperglycemia. This form of diabetes is caused by both genetic and environmental factors. Researchers have identified 10 genes that play a role in the development of Type 2 diabetes. TCF1LS; SLC3OA8; HHEX; PPARG; KCNJ11;IGF2B2; CDKAL1; CDKN2A; CDKN2B; FTO (known for the obesity). These genes are known to regulate the insulin action. The environmental factors that cause this type of diabetes is Age, heredity, Gender, Hypertension, Obesity, and Ethnicity, etc.
The mechanism for Type 2 diabetes include (Human Genome Project):
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