Defending Against Spoofing
There are a few precautions that can be taken to limit IP spoofing risks on your network, such as:
Filtering at the Router - Implementing ingress and egress filtering on your border routers is a great place to start your spoofing defence. You will need to implement an ACL (access control list) that blocks private IP addresses on your downstream interface. Additionally, this interface should not accept addresses with your internal range as the source, as this is a common spoofing technique used to circumvent firewalls. On the upstream interface, you should restrict source addresses outside of your valid range, which will prevent someone on your network from sending spoofed traffic to the Internet.
Encryption and Authentication - Implementing encryption and authentication will also reduce spoofing threats. Both of these features are included in Ipv6, which will eliminate current spoofing threats. Additionally, you should eliminate all host-based authentication measures, which are sometimes common for machines on the same subnet. Ensure that the proper authentication measures are in place and carried out over a secure (encrypted) channel.