Have you ever noticed a person with speech problems, weaker muscles, slower learning, different facial characteristics and slight buildup of tissue on the colored part of eye? That person may have Down Syndrome. Down Syndrome is a genetic disorder that occurs when an extra chromosome 21 is made at conception. The people who have Down Syndrome have cells with this extra chromosome 21 while people without Down Syndrome do not. Down Syndrome most often affects people of the Caucasian race.