Antiretroviral treatment usually elongates the lifespan of an HIV positive
person, it involves the use of certain drugs called antiretroviral drugs (
sometimes called anti-HIV drugs or HIV antiviral drugs). These drugs however
helps the immune system, by directing it on possible techniques of dealing with
the HIV virus, this is however not a cure for the disease. One of the common
Antiretroviral drug is the Azidothymidine (AZT). It is however,
being recommended that a minimum of three antiretroviral drugs should be
taken at a time for effective action, in what is know as the Highly Active
Antiretroviral Therapy (HAART or combination therapy).
ANTIRETROVIRAL DRUGS
Antiretroviral drugs are generally being classified
into various groups according to their actions and how they work. They
are:
Nucleoside analogues:
They are sometimes referred to as Nucleoside Reverse Transcriptase
Inhibitors (NRTIs). Its action is to slow down the production of the
reverse transcriptase( an enzyme needed by HIV to replicate) and make
HIV unable to infect cells and duplicate itself onto a persons DNA. This
set had being available as early as 1987.
non-nucleosides :
This group is also called Non-Nucleoside Reverse Transcriptase
Inhibitors (NNRTIs). They are also similar to the Nucleoside analogues,
the only difference is that the non - nucleoside analogue bind in a
different way to the cell's reverse transcriptase.
Protease Inhibitors:
This group blocks specific protease enzyme in infected cell from
reconstructing the virus and reproducing more HIV
Fusion Inhibitors:
This group is aimed at preventing HIV from entering cells, by
suppressing HIV replication.
In practicing antiretroviral treatment it is recommended that patients strictly
adhere to prescriptions.
In the plenary session of the XV international, there were lots of discussions, amongst the
discussions was possible ways of improving antiretroviral drugs.