Background

Background

There has been a resurgence of TB notably in the past decade. More than a century after the discovery of the bacillus causing tuberculosis by Robert Koch, TB remains a leading infectious disease killer. In the 19th and 20th centuries, there has been a steady decline in deaths from the disease in industrialised countries. This was given a boost by the development of antibiotics and other drugs to treat TB in the last 1940s. But the decline began to level out in the 1980s and since then the incidence of the disease has started to increase again and reached worrying levels by 1993.

In 1993, the World Health Organization (WHO) was concerned enough to declare tuberculosis a global emergency . It is estimated that between 2002 and 2020, approximately 1000 million people will be newly infected, over 150 million people will get sick, and 36 million will die of TB if control is not further strengthened. These are mind boggling figures!

So what has gone wrong? What are the factors leading to the resurgence of TB? These factors include the following:

HIV combined with TB is accelerating the spread of TB

  • Poor adherence to treatment and improperly managed TB programmes leading to the development of drug resistant TB particularly those multidrug-resistant TB
  • Mass global movement of people is helping the spread of TB
  • The prevalence of TB bacillus carriers. TB is the most common infection in the world. Almost one third of the world's population is infected with TB

Each of these factors will be described in detail in the following sections :

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